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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGFR4 All Species: 39.09
Human Site: Y690 Identified Species: 78.18
UniProt: P22455 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22455 NP_002002.3 802 87954 Y690 F T L G G S P Y P G I P V E E
Chimpanzee Pan troglodytes XP_518127 807 88293 T699 A A R N V L V T E D N V M K I
Rhesus Macaque Macaca mulatta XP_001087243 802 87975 Y690 F T L G G S P Y P G I P V E E
Dog Lupus familis XP_546211 858 94257 Y747 F T L G G S P Y P G I P V E E
Cat Felis silvestris
Mouse Mus musculus Q03142 799 88643 Y687 F T L G G S P Y P G I P V E E
Rat Rattus norvegicus Q498D6 800 88690 Y688 F T L G G S P Y P G I P V E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P18460 806 89712 Y689 F T L G G S P Y P G I P V E E
Frog Xenopus laevis Q91743 828 93399 Y713 F T L G G S P Y P V I P Y E E
Zebra Danio Brachydanio rerio Q90413 922 103447 Y801 F T L G G S P Y P G I P V E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07407 729 82568 L623 V W S Y G I L L W E I M T Y G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10656 1040 118938 Y875 M T L G G T P Y P T I A M P E
Sea Urchin Strong. purpuratus Q26614 972 110463 Y859 M T L G G T P Y P S V P V E Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.2 97.3 86.7 N.A. 89.7 88.7 N.A. N.A. 61.5 63.8 56.4 N.A. 35.5 N.A. 30.9 34.2
Protein Similarity: 100 89.7 98.3 88.5 N.A. 92.5 91.6 N.A. N.A. 72.9 74.6 68.6 N.A. 52.1 N.A. 46.1 49.2
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. N.A. 100 86.6 100 N.A. 13.3 N.A. 60 66.6
P-Site Similarity: 100 13.3 100 100 N.A. 100 100 N.A. N.A. 100 86.6 100 N.A. 13.3 N.A. 73.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 9 9 0 0 0 75 75 % E
% Phe: 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 84 92 0 0 0 0 59 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 0 0 84 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % K
% Leu: 0 0 84 0 0 9 9 9 0 0 0 0 0 0 0 % L
% Met: 17 0 0 0 0 0 0 0 0 0 0 9 17 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 84 0 84 0 0 75 0 9 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 9 0 0 67 0 0 0 9 0 0 0 0 0 % S
% Thr: 0 84 0 0 0 17 0 9 0 9 0 0 9 0 0 % T
% Val: 9 0 0 0 9 0 9 0 0 9 9 9 67 0 0 % V
% Trp: 0 9 0 0 0 0 0 0 9 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 84 0 0 0 0 9 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _